2005 Mules Football Schedule
| Date | Opponent | Time / Results |
| Aug. 25 | vs.
Adams (Colo.) State
 Game
NotesDownload Broadcast / Listen to Broadcast |
W, 14-6 (Recap) |
| Sept. 1 | vs. Lincoln (Mo.)
Game
Notes Download Broadcast / Listen to Broadcast |
W, 83-0 (Recap) |
| Sept. 10 | at Washburn University* (Topeka, Kan.)
Game
Notes Download Broadcast / Listen to Broadcast |
L, 42-27 (Recap) |
| Sept. 17 | vs. Truman State* (Family Day)
Game
Notes Download Broadcast / Listen to Broadcast |
W, 69-17 (Recap) |
| Sept. 24 | OPEN | ----- |
| Oct. 1 | at Missouri Western State University* (St. Joseph, Mo.)
Game
Notes Download Broadcast / Listen to Broadcast |
L, 13-10 (Recap) |
| Oct. 8 | at Southwest Baptist University*
(Bolivar, Mo.)
Game
Notes Download Broadcast / Listen to Broadcast |
W, 45-7 (Recap) |
| Oct. 15 | vs. Missouri Southern* (Homecoming)
Game
Notes Download Broadcast / Listen to Broadcast |
W, 27-24 (Recap) |
| Oct. 22 | at Northwest Missouri State University* (Maryville, Mo.)
Game
Notes |
L, 31-21 (Recap) |
| Oct. 29 | at Emporia State University * (Emporia, Kan.)
Game
Notes Download Broadcast / Listen to Broadcast |
W, 21-14 (Recap) |
| Nov. 5 | vs. Pittsburg State University*
Game
Notes Download Broadcast / Listen to Broadcast |
W, 83-21 (Recap) |
*MIAA game / Home games in bold